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SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells

AIM: To explore the effects of IκBα SUMOylation and NF-κB p65 deacetylation on NF-κB p65 activity induced by high glucose in cultured human lens epithelial cells (HLECs). METHODS: HLECs (SRA01/04) were cultured with 5.5, 25, and 50 mmol/L glucose media for 24h, and with 50 mmol/L glucose media for 0...

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Détails bibliographiques
Publié dans:Int J Ophthalmol
Auteurs principaux: Han, Xiao, Dong, Xiao-Xuan, Shi, Ming-Yu, Feng, Li, Wang, Xin-Ling, Zhang, Jin-Song, Yan, Qi-Chang
Format: Artigo
Langue:Inglês
Publié: International Journal of Ophthalmology Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739584/
https://ncbi.nlm.nih.gov/pubmed/31544029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2019.09.01
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