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DMBT1 inhibition of Pseudomonas aeruginosa twitching motility involves its N-glycosylation and cannot be conferred by the Scavenger Receptor Cysteine-Rich bacteria-binding peptide domain

The scavenging capacity of glycoprotein DMBT1 helps defend mucosal epithelia against microbes. DMBT1 binding to multiple bacterial species involves its conserved Scavenger Receptor Cysteine-Rich (SRCR) domains, localized to a 16-mer consensus sequence peptide, SRCRP2. Previously, we showed that DMBT...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Li, Jianfang, Wan, Stephanie J., Metruccio, Matteo M. E., Ma, Sophia, Nazmi, Kamran, Bikker, Floris J., Evans, David J., Fleiszig, Suzanne M. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739395/
https://ncbi.nlm.nih.gov/pubmed/31511582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49543-w
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