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Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance

Recent advance in cancer research sheds light on the contribution of mitochondrial respiration in tumorigenesis, as they efficiently produce ATP and oncogenic metabolites that will facilitate cancer cell growth. Here we show that a stabilizing factor for mitochondrial supercomplex assembly, COX7RP/C...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Suzuki, Takashi, Hobo, Rutsuko, Nakasato, Norie, Takeda, Satoru, Inoue, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739376/
https://ncbi.nlm.nih.gov/pubmed/31511525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12124-6
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