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PRIMARY ALDOSTERONISM: KCNJ5 MUTATIONS AND ADRENOCORTICAL CELL GROWTH

Aldosterone-producing adenomas (APA) with somatic mutations in the KCNJ5 potassium channel are a cause of primary aldosteronism. These mutations drive aldosterone excess but their role in cell growth is undefined. Our objective was to determine the role of KCNJ5 mutations in adrenal cell proliferati...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Yang, Yuhong, Gomez-Sanchez, Celso E., Jaquin, Diana, Prada, Elke Tatjana Aristizabal, Meyer, Lucie S., Knösel, Thomas, Schneider, Holger, Beuschlein, Felix, Reincke, Martin, Williams, Tracy Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739168/
https://ncbi.nlm.nih.gov/pubmed/31446799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13476
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