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Age- and sex-dependent effects of metformin on neural precursor cells and cognitive recovery in a model of neonatal stroke

Resident neural stem and progenitor cells, collectively termed neural precursor cells (NPCs), reside in a well-defined neurogenic niche in the subventricular zone (SVZ) and contribute to ongoing postnatal neurogenesis. It is well established that the NPC niche can alter the behavior of NPCs. NPC act...

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Publicat a:Sci Adv
Autors principals: Ruddy, Rebecca M., Adams, Kelsey V., Morshead, Cindi M.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739114/
https://ncbi.nlm.nih.gov/pubmed/31535024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax1912
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