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Partial demixing of RNA-protein complexes leads to intra-droplet patterning in phase-separated biological condensates

An emerging mechanism for intracellular organization is liquid-liquid phase separation (LLPS). Found in both the nucleus and the cytoplasm, liquid-like droplets condense to create compartments that are thought to promote and inhibit specific biochemistry. In this work, a multiphase, Cahn-Hilliard di...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Phys Rev E
Prif Awduron: Gasior, Kelsey, Zhao, Jia, McLaughlin, Grace, Forest, M. Gregory, Gladfelter, Amy S., Newby, Jay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739070/
https://ncbi.nlm.nih.gov/pubmed/30780260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.99.012411
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