Hypoxia Triggers SENP1 Modulation of Kruppel-Like Factor 15 and Transcriptional Regulation of Arginase 2 in Pulmonary Endothelium

OBJECTIVE: Kruppel-Like Factor 15 (KLF15) has recently been shown to suppress activation of proinflammatory processes that contribute to atherogenesis in vascular smooth muscle, however the role of KLF15 in vascular endothelial function is unknown. Arginase mediates inflammatory vasculopathy and vas...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Pandey, Deepesh, Nomura, Yohei, Rossberg, Max C., Hori, Daijiro, Bhatta, Anil, Keceli, Gizem, Leucker, Thorsten, Santhanam, Lakshmi, Shimoda, Larissa A., Berkowitz, Dan, Romer, Lewis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738933/
https://ncbi.nlm.nih.gov/pubmed/29472234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310660
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