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Proinflammatory Caspase A Activation and an Antiviral State Are Induced by a Zebrafish Perforin after Possible Cellular and Functional Diversification from a Myeloid Ancestor

In mammals, perforins play a central role in the granule-dependent cell death induced by natural killer T cells and cytotoxic T lymphocytes, and participate both in the defense against virus-infected and neoplastic cells and in the recognition of nonself molecules by the immune system. Little is kno...

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Detaylı Bibliyografya
Yayımlandı:J Innate Immun
Asıl Yazarlar: Varela, Mónica, Forn-Cuní, Gabriel, Dios, Sonia, Figueras, Antonio, Novoa, Beatriz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: S. Karger AG 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738880/
https://ncbi.nlm.nih.gov/pubmed/26087843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000431287
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