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HMGB1 Binds to Lipoteichoic Acid and Enhances TNF-a and IL-6 Production through HMGB1-Mediated Transfer of Lipoteichoic Acid to CD14 and TLR2

Lipoteichoic acid (LTA) is a component of the cell wall of Gram-positive bacteria and induces a toll-like receptor 2 (TLR2)-mediated inflammatory response upon initial binding to lipopolysaccharide-binding protein (LBP) and subsequent transfer to CD14. In this study, we identified a novel role for t...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Kwak, Man Sup, Lim, Mihwa, Lee, Yong Joon, Lee, Hyun Sook, Kim, Young Hun, Youn, Ju Ho, Choi, Ji Eun, Shin, Jeon-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738877/
https://ncbi.nlm.nih.gov/pubmed/25660311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000369972
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