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The Human Glycoprotein Salivary Agglutinin Inhibits the Interaction of DC-SIGN and Langerin with Oral Micro-Organisms

Salivary agglutinin (SAG), also known as gp340 or SALSA, is a glycoprotein encoded by the Deleted in Malignant Brain Tumours 1 gene and is abundantly present in human saliva. SAG aggregates bacteria and viruses, thereby promoting their clearance from the oral cavity. The mucosa lining the oral cavit...

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Publicat a:J Innate Immun
Autors principals: Boks, Martine A., Gunput, Sabrina T.G., Kosten, Ilona, Gibbs, Susan, van Vliet, Sandra J., Ligtenberg, Antoon J.M., van Kooyk, Yvette
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738800/
https://ncbi.nlm.nih.gov/pubmed/27082983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000443016
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