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LL-37 Triggers Formation of Streptococcus pyogenes Extracellular Vesicle-Like Structures with Immune Stimulatory Properties

Reports have shown that the antimicrobial peptide LL-37 is abundantly expressed but has limited bactericidal effect in Streptococcus pyogenes infections. At sub-inhibitory concentrations, LL-37 has been reported to alter virulence gene expression. Here, we explored the interaction of S. pyogenes str...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Uhlmann, Julia, Rohde, Manfred, Siemens, Nikolai, Kreikemeyer, Bernd, Bergman, Peter, Johansson, Linda, Norrby-Teglund, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738779/
https://ncbi.nlm.nih.gov/pubmed/26641861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000441896
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