Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells

Emerging evidence has shown that cinobufagin, as an active ingredient of Venenum Bufonis, inhibits tumor development. The aim of this study was to investigate the inhibitory effects of cinobufagin on A375 human malignant melanoma cells. MTT and colony formation assays showed that cinobufagin signifi...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Pan, Zhaohai, Zhang, Xin, Yu, Pengfei, Chen, Xiaoyu, Lu, Peng, Li, Minjing, Liu, Xiaona, Li, Zhipeng, Wei, Fei, Wang, Kejun, Zheng, Qiusheng, Li, Defang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738445/
https://ncbi.nlm.nih.gov/pubmed/31552178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00853
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