Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells

Emerging evidence has shown that cinobufagin, as an active ingredient of Venenum Bufonis, inhibits tumor development. The aim of this study was to investigate the inhibitory effects of cinobufagin on A375 human malignant melanoma cells. MTT and colony formation assays showed that cinobufagin signifi...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Pan, Zhaohai, Zhang, Xin, Yu, Pengfei, Chen, Xiaoyu, Lu, Peng, Li, Minjing, Liu, Xiaona, Li, Zhipeng, Wei, Fei, Wang, Kejun, Zheng, Qiusheng, Li, Defang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738445/
https://ncbi.nlm.nih.gov/pubmed/31552178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00853
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