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Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence
Although aging is considered to be an unavoidable event, recent experimental evidence suggests that the process can be counteracted. Intracellular calcium (Ca(2+)(i)) dyshomeostasis, mitochondrial dysfunction, oxidative stress, and lipid dysregulation are critical factors that contribute to senescen...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738398/ https://ncbi.nlm.nih.gov/pubmed/31467258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102191 |
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