The combination of complex karyotype subtypes and IGHV mutational status identifies new prognostic and predictive groups in chronic lymphocytic leukaemia

BACKGROUND: Complex karyotype (CK) is a heterogeneous category with a negative impact in chronic lymphocytic leukaemia (CLL). Our group has recently reported that CK patients with major structural abnormalities (i.e. CK2) are characterised by a worse prognosis, as compared to other lesions within CK...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Visentin, Andrea, Bonaldi, Laura, Rigolin, Gian Matteo, Mauro, Francesca Romana, Martines, Annalisa, Frezzato, Federica, Imbergamo, Silvia, Scomazzon, Edoardo, Pravato, Stefano, Bardi, Maria Antonella, Cavallari, Maurizio, Volta, Eleonora, Cavazzini, Francesco, Nanni, Maurizio, Del Giudice, Ilaria, Facco, Monica, Guarini, Anna, Semenzato, Gianpietro, Foà, Robin, Cuneo, Antonio, Trentin, Livio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738078/
https://ncbi.nlm.nih.gov/pubmed/31209327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0502-x
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