Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

BACKGROUND: Identification of biomarkers associated with benefit of adjuvant chemotherapy in stage II/III colon cancer is an important task. METHODS: Vessel density (VD) and tumour stroma were analysed in a randomised-trial-derived discovery cohort (n = 312) and in a stage II/III group of a populati...

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Udgivet i:Br J Cancer
Main Authors: Mezheyeuski, Artur, Hrynchyk, Ina, Herrera, Mercedes, Karlberg, Mia, Osterman, Eric, Ragnhammar, Peter, Edler, David, Portyanko, Anna, Ponten, Fredrik, Sjöblom, Tobias, Glimelius, Bengt, Östman, Arne
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738077/
https://ncbi.nlm.nih.gov/pubmed/31289351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0519-1
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