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WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest
WNT/β-catenin signaling is crucial for neural crest (NC) formation, yet the effects of the magnitude of the WNT signal remain ill-defined. Using a robust model of human NC formation based on human pluripotent stem cells (hPSCs), we expose that the WNT signal modulates the axial identity of NCs in a...
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| Publicado en: | Development |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737904/ https://ncbi.nlm.nih.gov/pubmed/31399472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.175604 |
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