Detection of RAS mutations in circulating tumor DNA: a new weapon in an old war against colorectal cancer. A systematic review of literature and meta-analysis

BACKGROUND: Tissue evaluation for RAS (KRAS or NRAS) gene status in metastatic colorectal cancer (mCRC) patients represent the standard of care to establish the optimal therapeutic strategy. Unfortunately, tissue biopsy is hampered by several critical limitations due to its invasiveness, difficulty...

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Bibliographic Details
Published in:Ther Adv Med Oncol
Main Authors: Galvano, Antonio, Taverna, Simona, Badalamenti, Giuseppe, Incorvaia, Lorena, Castiglia, Marta, Barraco, Nadia, Passiglia, Francesco, Fulfaro, Fabio, Beretta, Giordano, Duro, Giovanni, Vincenzi, Bruno, Tagliaferri, Pierosandro, Bazan, Viviana, Russo, Antonio
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
Subjects:
Meta-Analysis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737868/
https://ncbi.nlm.nih.gov/pubmed/31534493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919874653
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