Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis

Traumatic peritendinous fibrosis is a worldwide clinical problem resulting in severe limb disability. Hydroxycamptothecin (HCPT) is an anti-neoplastic drug widely exploited in clinical practice. It has shown potential of anti-fibrosis in recent years. We previously demonstrated that HCPT inhibited t...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Yao, Zhixiao, Wang, Wei, Ning, Jiexin, Zhang, Xiangqi, Zheng, Wei, Qian, Yun, Fan, Cunyi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737834/
https://ncbi.nlm.nih.gov/pubmed/31551777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00967
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