Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs

BACKGROUND: Moxidectin has previously shown limited efficacy (≤ 44.4%) against confirmed macrocyclic lactone (ML)-resistant Dirofilaria immitis strains at 3 µg/kg after single and multiple oral dosages. Three studies were conducted to evaluate higher oral moxidectin doses for efficacy against confir...

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Bibliographic Details
Published in:Parasit Vectors
Main Authors: McTier, Tom L., Six, Robert H., Pullins, Aleah, Chapin, Sara, Kryda, Kristina, Mahabir, Sean P., Woods, Debra J., Maeder, Steven J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737633/
https://ncbi.nlm.nih.gov/pubmed/31506088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3685-3
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