Pyridox (am) ine 5'-phosphate oxidase deficiency induces seizures in Drosophila melanogaster

Pyridox (am) ine 5'-phosphate oxidase (PNPO) is a rate-limiting enzyme in converting dietary vitamin B6 (VB6) to pyridoxal 5'-phosphate (PLP), the biologically active form of VB6 and involved in the synthesis of neurotransmitters including γ-aminobutyric acid (GABA), dopamine, and serotoni...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Chi, Wanhao, Iyengar, Atulya S R, Albersen, Monique, Bosma, Marjolein, Verhoeven-Duif, Nanda M, Wu, Chun-Fang, Zhuang, Xiaoxi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737294/
https://ncbi.nlm.nih.gov/pubmed/31261385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz143
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