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ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity

Dynamic control of thioredoxin (Trx) oxidoreductase activity is essential for balancing the need of cells to rapidly respond to oxidative/nitrosative stress and to temporally regulate thiol-based redox signaling. We have previously shown that cytokine stimulation of the respiratory epithelium induce...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kelleher, Zachary T., Wang, Chunbo, Forrester, Michael T., Foster, Matthew W., Marshall, Harvey E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737229/
https://ncbi.nlm.nih.gov/pubmed/31320475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007733
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