S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane

Junctophilins (JPH1–JPH4) are expressed in excitable and nonexcitable cells, where they tether endoplasmic/sarcoplasmic reticulum (ER/SR) and plasma membranes (PM). These ER/SR–PM junctions bring Ca-release channels in the ER/SR and Ca as well as Ca-activated K channels in the PM to within 10–25 nm....

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Jiang, Min, Hu, Junping, White, Frances K. H., Williamson, Judy, Klymchenko, Andrey S., Murthy, Akshay, Workman, Samuel W., Tseng, Gea-Ny
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737222/
https://ncbi.nlm.nih.gov/pubmed/31337710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006772
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