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Insights into the catalytic mechanism of a bacterial hydrolytic dehalogenase that degrades the fungicide chlorothalonil

Chlorothalonil (2,4,5,6-tetrachloroisophtalonitrile; TPN) is one of the most commonly used fungicides in the United States. Given TPN′s widespread use, general toxicity, and potential carcinogenicity, its biodegradation has garnered significant attention. Here, we developed a direct spectrophotometr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Xinhang, Bennett, Brian, Holz, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737215/
https://ncbi.nlm.nih.gov/pubmed/31331935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009094
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