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Onset kinetics of noise-induced purinergic adaptation of the ‘cochlear amplifier’

A major component of slowly reversible hearing loss which develops with sustained exposure to noise has been attributed to release of ATP in the cochlea activating P2X(2) receptor (P2X(2)R) type ATP-gated ion channels. This purinergic humoral adaptation is thought to enable the highly sensitive hear...

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Bibliographische Detailangaben
Veröffentlicht in:Purinergic Signal
Hauptverfasser: Cederholm, Jennie M. E., Ryan, Allen F., Housley, Gary D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737159/
https://ncbi.nlm.nih.gov/pubmed/31377959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09648-3
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