Serum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans

Disruption of the endothelial glycocalyx has a prominent role in the pathophysiology of sepsis. Developmental endothelial locus-1 (Del-1) is an endothelial-derived anti-inflammatory factor. We hypothesized that degradation of the endothelial glycocalyx during sepsis may increase serum Del-1. A mouse...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kim, Won-Young, Lee, Seung-Hwan, Kim, Dong-Young, Ryu, Hyun Jin, Chon, Gyu Rak, Park, Yun Young, Fu, Yan, Huh, Jin Won, Lim, Chae-Man, Koh, Younsuck, Choi, Eun Young, Hong, Sang-Bum
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737092/
https://ncbi.nlm.nih.gov/pubmed/31506547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49564-5
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