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Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling

L-lactate was long considered a glycolytic by-product but is now being recognized as a signaling molecule involved in cell survival. In this manuscript, we report the role of L-lactate in stress resistance and cell survival mechanisms using neuroblastoma cells (SH-SY5Y) as well as the C. elegans mod...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Tauffenberger, Arnaud, Fiumelli, Hubert, Almustafa, Salam, Magistretti, Pierre J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737085/
https://ncbi.nlm.nih.gov/pubmed/31506428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1877-6
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