Synergistic antifungal interactions of amphotericin B with 4-(5-methyl-1,3,4-thiadiazole-2-yl) benzene-1,3-diol

Amphotericin B (AmB) is a very potent antifungal drug with very rare resistance among clinical isolates. Treatment with the AmB formulations available currently is associated with severe side effects. A promising strategy to minimize the toxicity of AmB is reducing its dose by combination therapy wi...

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Publicado en:Sci Rep
Main Authors: Chudzik, Barbara, Bonio, Katarzyna, Dabrowski, Wojciech, Pietrzak, Daniel, Niewiadomy, Andrzej, Olender, Alina, Malodobry, Katarzyna, Gagoś, Mariusz
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737028/
https://ncbi.nlm.nih.gov/pubmed/31506532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49425-1
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