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Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress in vitro

BACKGROUND: The cellular and molecular response of liver cells to hypoxic stress is not fully understood. We used computational modeling to gain insights into the inflammatory response of primary human hepatocytes (HC) to hypoxic stress in vitro. METHODS: Primary HC from cancer patients were exposed...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Vodovotz, Yoram, Simmons, Richard L., Barclay, Derek, Yin, Jinling, Jefferson, Bahiyyah S., Zamora, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736831/
https://ncbi.nlm.nih.gov/pubmed/31555685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.07.09
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