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Assessing Pharmacokinetic Marker Correlates of Outcome, with Application to Antibody Prevention Efficacy Trials
The Antibody Mediated Prevention (AMP) efficacy trials are the first studies to evaluate whether passive administration of a broadly neutralizing monoclonal antibody (mAb) can prevent HIV acquisition. The trials randomize 4600 HIV-negative volunteers to receive 10 infusions of the mAb VRC01 or place...
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| Veröffentlicht in: | Stat Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736712/ https://ncbi.nlm.nih.gov/pubmed/31313349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8310 |
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