A Cytosolic Sensor, PmDDX41, Binds Double Stranded-DNA and Triggers the Activation of an Innate Antiviral Response in the Shrimp Penaeus monodon via the STING-Dependent Signaling Pathway

Helicase DDX41 is a cytosolic sensor capable of detecting double-stranded DNA in mammals. However, the function of DDX41 remains poorly understood in invertebrates. In a previous study, we identified the first DDX41 sensor in the black tiger shrimp Penaeus monodon (PmDDX41) and showed that it played...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Soponpong, Suthinee, Amparyup, Piti, Kawai, Taro, Tassanakajon, Anchalee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736559/
https://ncbi.nlm.nih.gov/pubmed/31552028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02069
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