載入...

N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels

AIMS: Elevated apolipoprotein C-III (apoC-III) levels are associated with hypertriglyceridaemia and coronary heart disease. AKCEA-APOCIII-L(Rx) is an N-acetyl galactosamine-conjugated antisense oligonucleotide targeted to the liver that selectively inhibits apoC-III protein synthesis. METHODS AND RE...

全面介紹

Na minha lista:
書目詳細資料
發表在:Eur Heart J
Main Authors: Alexander, Veronica J, Xia, Shuting, Hurh, Eunju, Hughes, Steven G, O’Dea, Louis, Geary, Richard S, Witztum, Joseph L, Tsimikas, Sotirios
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736334/
https://ncbi.nlm.nih.gov/pubmed/31329855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz209
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!