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DREADD technology reveals major impact of G(q) signalling on cardiac electrophysiology

AIMS: Signalling via Gq-coupled receptors is of profound importance in many cardiac diseases such as hypertrophy and arrhythmia. Nevertheless, owing to their widespread expression and the inability to selectively stimulate such receptors in vivo, their relevance for cardiac function is not well unde...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Kaiser, Elisabeth, Tian, Qinghai, Wagner, Michael, Barth, Monika, Xian, Wenying, Schröder, Laura, Ruppenthal, Sandra, Kaestner, Lars, Boehm, Ulrich, Wartenberg, Philipp, Lu, Huiyan, McMillin, Sara M, Bone, Derek B J, Wess, Jürgen, Lipp, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736079/
https://ncbi.nlm.nih.gov/pubmed/30321287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy251
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