Enzyme-free optical DNA mapping of the human genome using competitive binding

Optical DNA mapping (ODM) allows visualization of long-range sequence information along single DNA molecules. The data can for example be used for detecting long range structural variations, for aiding DNA sequence assembly of complex genomes and for mapping epigenetic marks and DNA damage across th...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Müller, Vilhelm, Dvirnas, Albertas, Andersson, John, Singh, Vandana, KK, Sriram, Johansson, Pegah, Ebenstein, Yuval, Ambjörnsson, Tobias, Westerlund, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Methods Online
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735870/
https://ncbi.nlm.nih.gov/pubmed/31165870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz489
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