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Enzyme-free optical DNA mapping of the human genome using competitive binding

Optical DNA mapping (ODM) allows visualization of long-range sequence information along single DNA molecules. The data can for example be used for detecting long range structural variations, for aiding DNA sequence assembly of complex genomes and for mapping epigenetic marks and DNA damage across th...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Müller, Vilhelm, Dvirnas, Albertas, Andersson, John, Singh, Vandana, KK, Sriram, Johansson, Pegah, Ebenstein, Yuval, Ambjörnsson, Tobias, Westerlund, Fredrik
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735870/
https://ncbi.nlm.nih.gov/pubmed/31165870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz489
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