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DNA sequence models of genome-wide Drosophila melanogaster Polycomb binding sites improve generalization to independent Polycomb Response Elements

Polycomb Response Elements (PREs) are cis-regulatory DNA elements that maintain gene transcription states through DNA replication and mitosis. PREs have little sequence similarity, but are enriched in a number of sequence motifs. Previous methods for modelling Drosophila melanogaster PRE sequences (...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Bredesen, Bjørn André, Rehmsmeier, Marc
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735708/
https://ncbi.nlm.nih.gov/pubmed/31340029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz617
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