MTBP regulates cell survival and therapeutic sensitivity in TP53 wildtype glioblastomas

Background: Glioblastoma (GBM) is highly proliferative and resistant to radio-chemotherapy. Loss of tumor suppressor gene TP53 function frequently occurs at protein level in GBMs. This inhibition is often mediated by other components within the p53 signaling axis, including MDM2, whose binding prote...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Song, Yifu, Zhang, Li, Jiang, Yang, Hu, Tianhao, Zhang, Di, Qiao, Qiao, Wang, Run, Wang, Minghao, Han, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735364/
https://ncbi.nlm.nih.gov/pubmed/31534534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35747
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