Resolving MiSeq-Generated Ambiguities in HLA-DPB1 Typing by Using the Oxford Nanopore Technology

The technical limitations of current next-generation sequencing technologies, combined with an ever-increasing number of human leukocyte antigen (HLA) alleles, form the basis for the additional ambiguities encountered at an increasing rate in clinical practice. HLA-DPB1 characterization, particularl...

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Gepubliceerd in:J Mol Diagn
Hoofdauteurs: Duke, Jamie L., Mosbruger, Timothy L., Ferriola, Deborah, Chitnis, Nilesh, Hu, Taishan, Tairis, Nikolaos, Margolis, David J., Monos, Dimitri S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734860/
https://ncbi.nlm.nih.gov/pubmed/31173929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2019.04.009
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