Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

BACKGROUND: Approximately 4% of colorectal cancer (CRC) patients have at least two simultaneous cancers in the colon. Due to the shared environment, these synchronous CRCs (SCRCs) provide a unique setting to study colorectal carcinogenesis. Understanding whether these tumours are genetically similar...

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發表在:Br J Cancer
Main Authors: Hänninen, Ulrika A., Wirta, Erkki-Ville, Katainen, Riku, Tanskanen, Tomas, Hamberg, Jiri, Taipale, Minna, Böhm, Jan, Renkonen-Sinisalo, Laura, Lepistö, Anna, Forsström, Linda M., Pitkänen, Esa, Palin, Kimmo, Seppälä, Toni T., Mäkinen, Netta, Mecklin, Jukka-Pekka, Aaltonen, Lauri A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734647/
https://ncbi.nlm.nih.gov/pubmed/30894686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0427-4
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