Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPB(y/y) mice model

BACKGROUND: The basal transcription/repair factor TFIIH is a ten sub-unit complex essential for RNA polymerase II (RNAP2) transcription initiation and DNA repair. In both these processes TFIIH acts as a DNA helix opener, required for promoter escape of RNAP2 in transcription initiation, and to set t...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Donnio, Lise-Marie, Miquel, Catherine, Vermeulen, Wim, Giglia-Mari, Giuseppina, Mari, Pierre-Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734240/
https://ncbi.nlm.nih.gov/pubmed/31516394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0945-4
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