Effects of two isometheptene enantiomers in isolated human blood vessels and rat middle meningeal artery – potential antimigraine efficacy

BACKGROUND: Racemic isometheptene [(RS)-isometheptene] is an antimigraine drug that due to its cardiovascular side-effects was separated into its enantiomers, (R)- and (S)-isometheptene. This study set out to characterize the contribution of each enantiomer to its vasoactive profile. Moreover, rat n...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Headache Pain
Auteurs principaux: Labastida-Ramírez, Alejandro, Rubio-Beltrán, Eloísa, Haanes, Kristian A., de Vries, René, Dammers, Ruben, Bogers, A. J. J. C., van den Bogaerdt, Antoon, Daugherty, Bruce L., Danser, Alexander H. J., Villalón, Carlos M., MaassenVanDenBrink, Antoinette
Format: Artigo
Langue:Inglês
Publié: Springer Milan 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734216/
https://ncbi.nlm.nih.gov/pubmed/31053059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-019-1003-2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires