Novel Mechanisms for IGF-I Regulation by Glucagon in Carp Hepatocytes: Up-Regulation of HNF1α and CREB Expression via Signaling Crosstalk for IGF-I Gene Transcription

Glucagon, a key hormone for glucose homeostasis, can exert functional crosstalk with somatotropic axis via modification of IGF-I expression. However, its effect on IGF-I regulation is highly variable in different studies and the mechanisms involved are largely unknown. Using grass carp as a model, t...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Bai, Jin, Jiang, Xue, He, Mulan, Chan, Ben C. B., Wong, Anderson O. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734168/
https://ncbi.nlm.nih.gov/pubmed/31551932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00605
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