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Yeast PAF1 complex counters the pol III accumulation and replication stress on the tRNA genes
The RNA polymerase (pol) III transcribes mostly short, house-keeping genes, which produce stable, non-coding RNAs. The tRNAs genes, highly transcribed by pol III in vivo are known replication fork barriers. One of the transcription factors, the PAF1C (RNA polymerase II associated factor 1 complex) i...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733944/ https://ncbi.nlm.nih.gov/pubmed/31501524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49316-5 |
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