Human multipotent hematopoietic progenitor cell expansion is neither supported in endothelial and endothelial/mesenchymal co-cultures nor in NSG mice

Endothelial and mesenchymal stromal cells (ECs/MSCs) are crucial components of hematopoietic bone marrow stem cell niches. Both cell types appear to be required to support the maintenance and expansion of multipotent hematopoietic cells, i.e. hematopoietic stem cells (HSCs) and multipotent progenito...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Radtke, Stefan, Görgens, André, da Conceição Castro, Symone Vitoriano, Kordelas, Lambros, Köninger, Angela, Dürig, Jan, Möllmann, Michael, Horn, Peter A., Giebel, Bernd
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733927/
https://ncbi.nlm.nih.gov/pubmed/31501490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49221-x
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