TM4SF5-mediated CD44v8-10 splicing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis

Reactive oxygen species (ROS) regulate cell fate, although signaling molecules that regulate ROS hormesis remain unclear. Here we show that transmembrane 4 L six family member 5 (TM4SF5) in lung epithelial cells induced the alternatively spliced CD44v8-10 variant via an inverse ZEB2/epithelial splic...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Kim, Ji Eon, Kim, Hye-Jin, Jung, Jae Woo, Song, Dae-Geun, Park, Dasomi, Lee, Haesong, Um, Hyejin, Park, Jinsoo, Nam, Seo Hee, Cho, Moonjae, Lee, Jung Weon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733838/
https://ncbi.nlm.nih.gov/pubmed/31501417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1878-5
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