Identification of Multiple Potent Neutralizing and Non-Neutralizing Antibodies against Epstein-Barr Virus gp350 Protein with Potential for Clinical Application and as Reagents for Mapping Immunodominant Epitopes

Prevention of Epstein-Barr virus (EBV) infection has focused on generating neutralizing antibodies (nAbs) targeting the major envelope glycoprotein gp350/220 (gp350). In this study, we generated 23 hybridomas producing gp350-specific antibodies. We compared the candidate gp350-specific antibodies to...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Mutsvunguma, Lorraine Z, Rodriguez, Esther, Escalante, Gabriela M, Muniraju, Murali, Williams, John C, Warden, Charles, Qin, Hanjun, Wang, Jinhui, Wu, Xiwei, Barasa, Anne, Mulama, David H, Mwangi, Waithaka, Ogembo, Javier Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733660/
https://ncbi.nlm.nih.gov/pubmed/31377598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.07.026
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