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Mechanisms of Gemcitabine Oral Absorption as Determined by In Situ Intestinal Perfusions in Mice
Gemcitabine is a widely used chemotherapeutic drug that is administered via intravenous infusion due to a low oral bioavailability of only 10%. This low oral bioavailability is believed to be the result of gemcitabine’s low intestinal permeability and oral absorption, followed by significant presyst...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733655/ https://ncbi.nlm.nih.gov/pubmed/31207211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.06.013 |
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