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Endothelial-to-mesenchymal transition: pathogenesis and therapeutic targets for chronic pulmonary and vascular diseases

Endothelial-to-mesenchymal transition (EndoMT) is a process of transdifferentiation where endothelial cells gradually adopt the phenotypic characteristics of mesenchymal cells. This phenomenon was first discovered in embryonic heart development. The mechanisms underlying EndoMT are due to the activa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Pharmacol
Hauptverfasser: Lu, Xuexin, Gong, Jiannan, Dennery, Phyllis A., Yao, Hongwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733623/
https://ncbi.nlm.nih.gov/pubmed/31251941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.06.021
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