CCR2 knockout ameliorates obesity-induced kidney injury through inhibiting oxidative stress and ER stress

CCL2/CCR2 signaling is believed to play an important role in kidney diseases. Several studies have demonstrated that blocking of CCR2 has a therapeutic effect on kidney diseases. However, the effects of CCR2 knockout on obesity-induced kidney injury remain unclear. We investigated the therapeutic ef...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Lee, Seung Joo, Kang, Jeong Suk, Kim, Hong Min, Lee, Eun Soo, Lee, Ji-Hye, Chung, Choon Hee, Lee, Eun Young
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733486/
https://ncbi.nlm.nih.gov/pubmed/31498850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222352
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