Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

Genomic rearrangements (gross chromosomal rearrangements, GCRs) threatens genome integrity and cause cell death or tumor formation. At the terminus of linear chromosomes, a telomere-binding protein complex, called shelterin, ensures chromosome stability by preventing chromosome end-to-end fusions an...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Irie, Hiroyuki, Yamamoto, Io, Tarumoto, Yusuke, Tashiro, Sanki, Runge, Kurt W., Ishikawa, Fuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733473/
https://ncbi.nlm.nih.gov/pubmed/31454352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008335
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