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Protein Kinase D1 Conditional Null Mice Show Minimal Bone Loss following Ovariectomy

We previously found that 3- and 6-month-old male mice with conditional ablation of protein kinase D1 (PRKD1) in osteoprogenitor cells (expressing Osterix) exhibited reduced bone mass. Others have demonstrated similar effects in young female PRKD1-deficient mice. Here we examined the bone resorptive...

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Bibliografski detalji
Izdano u:Mol Cell Endocrinol
Glavni autori: Bollag, Wendy B., Ding, Ke-Hong, Choudhary, Vivek, Xu, Jianrui, Zhong, Qing, Elsayed, Ranya, Bailey, Lakiea J., Elsalanty, Mohammed, Yu, Kanglun, Johnson, Maribeth H., McGee-Lawrence, Meghan E., Isales, Carlos M.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733406/
https://ncbi.nlm.nih.gov/pubmed/29530783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2018.03.006
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