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Model-based approach to the design of pharmaceutical roller-compaction processes

This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throughput experiments as input. This low-throughput data is utilized in an iter...

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Detalhes bibliográficos
Publicado no:Int J Pharm X
Main Authors: Toson, Peter, Lopes, Diogo G., Paus, Raphael, Kumar, Ashish, Geens, Jeroen, Stibale, Sandy, Quodbach, Julian, Kleinebudde, Peter, Hsiao, Wen-Kai, Khinast, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733294/
https://ncbi.nlm.nih.gov/pubmed/31517270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2019.100005
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